In this 2011 trial, resistance exercise is shown to reduce liver fat content even in the absence of weight loss. Resistance exercise improves muscle’s ability to effectively regulate circulating glucose and fat levels, a change that reduces insulin resistance and liver fat buildup. At minimum, this indicates resistance exercise alone may help reverse insulin resistance and fatty liver disease. More importantly, it suggests treatments that induce weight loss, such as other changes to diet and exercise, may drive more rapid and effective metabolic improvements when paired with resistance training.