Prof. Tim Noakes describes Gerald Reaven’s research on the carbohydrate metabolisms of patients with coronary heart disease (CHD), which demonstrated patients with hypertriglyceridemia were more likely to be insulin resistant. Noakes also highlights a series of studies conducted by Reaven and colleagues that explored the effects of high- and low-carbohydrate diets on blood triglyceride concentrations — studies that ultimately revealed the American Diabetes Association’s high-carb, low-fat dietary recommendations may have been increasing diabetics’ risk of CHD.