In this expansive lecture, delivered at CrossFit Headquarters on March 9, 2019, Dr. Robert Lustig explores the lacuna that has emerged between medical research and policy, specifically as they pertain to metabolic disease. Via a review of recent scientific literature, Lustig dispels a series of myths about metabolic disease, including the myths that obesity is the problem and that all calories are equal in their effect on human metabolism. Delivering on his intention to “translate the science into rational and effective policy,” he concludes by offering a series of propositions for halting the corruption of healthcare and the health sciences at the hands of profit-driven multinational corporations.