Tuesday

191008

Hypertriglyceridemia, Atherogenic Dyslipidemia, and the Metabolic Syndrome

This highly cited 1998 review links insulin resistance to increased heart disease risk. Dr. Scott Grundy, the review author, observed the “lipid triad” of high triglycerides, small LDL particles, and low HDL is common among those with metabolic syndrome and insulin resistance. These conditions may also be mechanistically linked. Insulin resistance leads to increased liver fat, which increases fat VLDL production — in other words, insulin resistance may directly cause the lipid triad.

Read MoreHypertriglyceridemia, Atherogenic Dyslipidemia, and the Metabolic Syndrome